Inter start Hakan Calhanoglu, Andy Diouf and Francesco Pio Esposito in their final pre-season test with Real Betis, while John Stones is on the bench hoping for his debut.
It kicks off at the Stadio San Nicola in Bari at 18.30 UK time (19.30 CEST).
The Nerazzurri go into the new campaign fresh from a Double of the Scudetto and Coppa Italia, so hope to build on that success going forward.
It has taken longer than expected to replace departing Denzel Dumfries, Francesco Acerbi and Matteo Darmian, though Stones is on the bench and Djed Spence ought to announce his transfer from Tottenham Hotspur today.
Lautaro Martinez is rested after taking Argentina to the World Cup Final, so Ange-Yoan Bonny partners Pio Esposito upfront.
Andy Diouf takes the wide right role while waiting for Spence to come in.
Real Betis have qualified for the Champions League after finishing fifth in LaLiga last season, and reached the Conference League Final in 2024.
Inter vs. Real Betis line-ups
Inter: J Martinez; Bisseck, Bovio, Bastoni; Diouf, Barella, Calhanoglu, Zielinski, Carlos Augusto; Bonny, Esposito
Real Betis: Valles; Bellerin, Bartra, Natan, Fran Garcia; Facundo Bernal, Marc Roca; Antony, Fornals, Riquelme; Hernandez
